TOP LATEST FIVE LDN-27219 SIDE EFFECTS URBAN NEWS

One particularly attention-grabbing compound is LDN-27219. When most tTG inhibitors are designed to bind into the protein crosslinking Energetic site, LDN-27219 in its place binds on the nucleotide binding pocket in the enzyme while it is actually in its closed-condition conformation, and stabilizes that conformation to stop crosslinking activity.7